The ALG2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ALG2, and ALG2 alpha-1,3/1,6-mannosyltransferase. This antibody recognizes Human, Mouse, and Rat antigen. The ALG2 Polyclonal Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1, 3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants